World No 1 Best selling Arpolax(Citalopram) Tablet

World No 1 Best selling Arpolax(Citalopram) Tablet

Arpolax(Citalopram)

Therapeutic Group: Drugs of Nervous System

Presentation

Arpolax tablet: Each tablet contains Citalopram Hydrobromide INN equivalent to Citalopram 20 mg.

Description

Citalopram is an orally administered selective serotonin reuptake inhibitor (SSRI) with a chemical structure unrelated to that of other SSRIs, tricyclic, tetracyclic or other available antidepressant agents. The mechanism of action of Citalopram as an antidepressant is presumed to be linked to potentiation of serotonergic activity in central nervous system resulting from its inhibition of CNS neuronal reuptake of serotonin (5-HT).

Indications

Citalopram is indicated for depressive illness and panic disorder. It is also indicated in substance abuse disorders and alcohol dependence. Citalopram has also been given in variety of anxiety disorders including obsessive-compulsive disorder and social phobia. It is also effective in generalized anxiety disorder, post-traumatic stress disorder, premenstrual syndrome, idiopathic Parkinson’s disease and eating disorder.

Dosage & Administration

Depressive illness 20 mg daily as a single dose in the morning or evening; increased if
necessary to maximum 60 mg daily (Elderly maximum 40 mg
daily).
Panic disorder Initially 10 mg daily, increased to 20 mg after 7 days; usual dose 20-
30 mg daily; maximum 60 mg daily (Elderly maximum 40 mg
daily).

Side Effects

SSRIs are less sedating and have fewer antimuscarinic and cardiotoxic effects than tricyclic antidepressants. However, side-effects may be seen, includes gastro-intestinal effects (nausea, vomiting, dyspepsia, abdominal pain, diarrhoea, constipation), anorexia with weight loss, palpitations, tachycardia, postural hypotension, cough, confusion, impaired concentration, amnesia, urinary retention, sweating, movement disorders, urticaria, anaphylaxis, arthralgia, myalgia and photosensitivity.

Precautions

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Caution should be taken in patients with epilepsy, concurrent electroconvulsive therapy, history of mania, cardiac disease, diabetes mellitus, angle-closure glaucoma, history of bleeding disorders, hepatic and renal impairment. Abrupt withdrawal of Citalopram should be avoided.

Use in Pregnancy & Lactation

Pregnancy
There are no adequate and well-controlled studies in pregnant women; therefore, Citalopram should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Lactation
Citalopram is excreted in human breast milk. So, the decision whether to continue or discontinue either nursing or Citalopram therapy should take into account the risks of Citalopram exposure for the infants and the benefits of Citalopram treatment for the mother.

Drug Interaction

Ketoconazole, Itraconazole or Macrolide antibiotics and Citalopram co-administration decreases the metabolism of Citalopram. Omeprazole and Citalopram co-administration might decrease the clearance of Citalopram.

Over Dose

It is a very safe drug. There were no reports of fatal Citalopram overdose in clinical trials involving overdoses of up to 2000 mg.

Commercial Pack

Arpolax tablet: Box containing 3 blister strips of 10 tablets.

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FAQ: 

  1. What are side effects of citalopram?

Answer : Citalopram may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • stomach pain.
  • decreased appetite.
  • weight loss.
  1. What are the worst side effects of citalopram?

Answer : Serious side effects and their symptoms can include the following:

  • Suicidal thoughts or actions. Symptoms can include: …
  • Heart rhythm changes (QT prolongation and Torsade de Pointes). Symptoms can include: …
  • Serotonin syndrome. Symptoms can include: …
  • Visual problems. …
  • Low salt (sodium) levels in the blood.
  1. Is citalopram used for anxiety?

Answer : Citalopram (generic Celexa) is an inexpensive antidepressant medication used to treat anxiety. While it can help with your anxiety, it may take a few weeks for your symptoms to get better, so try to be patient. You may experience some side effects while taking Celexa, but these are generally mild.

 

  1. Is citalopram the same as Xanax?

Answer : No. You might experience some of the same side effects while taking Xanax or Celexa (citalopram), but the two medications belong to different medication classes. Celexa (citalopram) is a selective serotonin reuptake inhibitor (SSRI), while Xanax is a benzodiazepine.

 

  1. Is citalopram better than Prozac?

Answer : Is Celexa or Prozac more effective? A study compared Celexa and Prozac and found both medications to be well-tolerated. The study concluded that Celexa was as effective as Prozac to treat depression, and patients who took Celexa started to feel better faster than patients who took Prozac.

 

  1. Is it best to take citalopram morning or night?

Answer : You can take citalopram at any time of day, as long as you stick to the same time every day. If you have trouble sleeping, it’s best to take it in the morning.

 

  1. What drugs should not be taken with citalopram?

Answer : Do not use citalopram with buspirone (Buspar®), fentanyl (Abstral®, Duragesic®), lithium (Eskalith®, Lithobid®), methylene blue injection, tryptophan, St John’s wort, amphetamines, or some pain or migraine medicines (eg, rizatriptan, sumatriptan, tramadol, Frova®, Imitrex®, Maxalt®, Relpax®, Ultram®, Zomig®).

 

  1. Does citalopram calm you down?

Answer : What will citalopram do? Citalopram should help you feel calm and relaxed. It could take some time for citalopram to have its full effect. This effect should reduce your behaviour problem.

 

  1. Can citalopram make you feel weird?

Answer : If you feel restless or feel like you cannot keep still, go to your doctor. If you keep on taking more citalopram each day, it may make these feelings worse (see section 5). Talk to your doctor before you stop taking citalopram. If you stop taking it suddenly or miss a dose you may get unwanted effects (see section 4).

 

  1. Is 10 mg of antidepressant a lot?

Answer : Dependent on individual patient response, the dose may be increased to a maximum of 40 mg daily. Patients should be started on 10 mg/day and the dose gradually increased in 10 mg steps according to the patient’s response up to the recommended dose. The recommended dose is 20-30 mg daily.

  1. How long can you stay on citalopram?

Answer : The long-term use of citalopram is safe when people take it as their doctor prescribes. However, research indicates that using any antidepressant for more than 6 weeks can cause withdrawal symptoms on tapering or stopping the drug

 

  1. What happens if you drink alcohol while taking citalopram?

Answer : citalopram food

Alcohol can increase the nervous system side effects of citalopram such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with citalopram.

 

  1. What does 20 mg of citalopram do?

Answer : Citalopram is used to treat depression. It may improve your energy level and feelings of well-being. Citalopram is known as a selective serotonin reuptake inhibitor (SSRI). This medication works by helping to restore the balance of a certain natural substance (serotonin) in the brain.

 

  1. Does citalopram help with social anxiety?

Answer : Citalopram treatment may benefit patients with primary social anxiety disorder and comorbid major depression, and it should be further studied in controlled trials.

 

  1. Which is the best SSRI for anxiety?

Answer : The only SSRIs that are currently FDA-approved for this condition are sertraline (Zoloft) and immediate- and extended-release paroxetine (Paxil, Paxil CR). Extended-release venlafaxine (Effexor XR) — a serotonin and norepinephrine reuptake inhibitor (SNRI) — is also FDA-approved to treat social anxiety disorder.

 

  1. What is the best antidepressant?

Answer : When the researchers checked which depression drugs were tolerated the best, these topped the list:

  • Celexa (citalopram)
  • Lexapro (escitalopram)
  • Prozac (fluoxetine)
  • Trintellix (vortioxetine)
  • Zoloft (sertraline)
  1. Is Prozac or Lexapro better?

Answer : When comparing Lexapro to Prozac, the authors found both drugs to be similarly effective. Another study, which was a review of many studies, compared antidepressants and initially found Lexapro to possibly be more effective and better tolerated than other antidepressants

 

  1. Does Lexapro calm you down?

Answer : Escitalopram belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRI). It may improve your energy level and feelings of well-being and decrease nervousness.

 

  1. Can I drink coffee with citalopram?

Answer : Citalopram Interactions with Caffeine

Consumption of caffeine products, chocolates and desserts along with citalopram can cause dangerous side effects leading to serotonin syndrome. So, avoid desserts with chocolate while taking citalopram.

 

  1. Is there a better antidepressant than citalopram?

Answer : The benefits of escitalopram compared with citalopram, as demonstrated by both magnitude of effect and time of onset, are superior to the benefits of citalopram, an antidepressant drug with proven efficacy. This evidence clearly supports the use of escitalopram as a legitimate first-line treatment for MDD.

 

  1. Which is the safest antidepressant?

Answer : Citalopram and escitalopram have been considered the safest among the SSRIs with respect to potential for liver injury [41].

 

  1. Is citalopram well tolerated?

Answer : Citalopram 20 mg, 40 mg and 60 mg are all effective and well tolerated compared with placebo in obsessive-compulsive disorder. Int Clin Psychopharmacol.

 

  1. Can I take ibuprofen with citalopram?

Answer : Using citalopram together with ibuprofen may increase the risk of bleeding. The interaction may be more likely if you are elderly or have kidney or liver disease. Talk to your doctor if you have any questions or concerns.

 

  1. Can u take citalopram with Xanax?

Answer : Using ALPRAZolam together with citalopram may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.

 

  1. Can you take vitamins while on citalopram?

Answer : No interactions were found between citalopram and Vitamin B12. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

 

  1. What painkillers can you take with citalopram?

Answer : If you need to take a painkiller it’s fine to take paracetamol with citalopram. However, don’t take anti-inflammatory painkillers such as ibuprofen, diclofenac or naproxen without checking with your doctor first, because these may increase the risk of bleeding

 

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