Best selling Ciprofloxacin, Ciprofloxacin side effects, ciprofloxacin uti and more

Beuflox(Ciprofloxacin)

Presentation

Beuflox 250: Each film-coated tablet contains Ciprofloxacin Hydrochloride USP equivalent to Ciprofloxacin 250 mg.

Beuflox 500: Each film-coated tablet contains Ciprofloxacin Hydrochloride USP equivalent to Ciprofloxacin 500 mg.

Beuflox 750: Each film-coated tablet contains Ciprofloxacin Hydrochloride USP equivalent to Ciprofloxacin 750 mg.

Beuflox 250 Granules for suspension: Each sachet contains Ciprofloxacin USP 250 mg.

Beuflox 125 Granules for suspension: Each sachet contains Ciprofloxacin USP 125 mg.

Beuflox Granules for suspension 60 ml: Each 5 ml contains Ciprofloxacin USP 250 mg.

Beuflox IV Infusion 100 ml: Each 100 ml solution contains Ciprofloxacin Lactate equivalent to Ciprofloxacin BP 200 mg.

Description

Ciprofloxacin is a synthetic 4-quinolone derivative with bactericidal activity against a wide range of gram-positive and gram-negative organism. It is active against most gram-negative aerobic bacteria including Enterobacteriaceae and Pseudomonas aeruginosa. Ciprofloxacin is also active against gram-positive aerobic bacteria including penicillinase producing, non-penicillinase producing and methicillin resistant Staphylococci. However many strains of Streptococci are relatively resistant to the drug. The bactericidal activity of Ciprofloxacin results from interference with the enzyme DNA gyrase needed for the synthesis of bacterial DNA. The mode of action of Ciprofloxacin is different from other antibiotics like penicillins, cephalosporins, aminoglycosides, tetracyclines and for this reason it is observed that organisms resistant to these antibiotics are susceptible to Ciprofloxacin. Ciprofloxacin is well absorbed from the GIT after oral administration and it is widely distributed into the body tissues and fluid. The half-life of Ciprofloxacin is 3.5 – 4.5 hours. About 30-50% of an oral dose of Ciprofloxacin is excreted in the urine within 24 hours as unchanged drug and active metabolites.

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Indications

Ciprofloxacin is indicated for the treatment of the following infections caused by sensitive bacteria:

Severe systemic infections: e.g; septicemia, bacteremia, peritonitis, infections in immunosuppressed patients with haematological or solid tumors and in patients in intensive care unit with specific problems such as infected burns.

Respiratory tract infections: Lobar and broncho pneumonia, acute and chronic bronchitis and empyema.

Urinary tract infections: Uncomplicated and complicated urethritis, cystitis, pyelonephritis, prostatitis and epididymitis.

Skin and soft tissue infections: Infected ulcers, wound infections, abscesses, cellulitis, otitis externa, erysipelas and infected burns.

Gastrointestinal infections: Enteric fever, infective diarrhea.

Infections of the biliary tract: Cholangitis, cholecystitis, empyema of the gall bladder.

Intra-abdominal infections: Peritonitis, intra abdominal abscesses.

Bone and joint infections: Osteomyelitis, septic arthritis.

Pelvic infections: Salpingitis, endometritis, pelvic inflammatory diseases.

Eye, ear, nose and throat infections: Otitis media, sinusitis, mastoiditis, tonsillitis.

Gonorrhoea: Urethral, rectal and pharyngeal gonorrhoea caused by beta-lactamase producing organism or organisms moderately sensitive to penicillin.

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Dosage & Administration

Adult Dose:
For oral dosage &suspension:
Urinary Tract infection: Acute uncomplicated: 250 mg twice daily for 3 days; Mild/Moderate: 250 mg twice daily for 7 to 14 days; Severe/Complicated: 500 mg twice daily for 7 to 14 days; Chronic Bacterial Prostitis : 500 mg twice daily for 28 days; Lower Respiratory Tract infection: Mild/Moderate: 500 mg twice daily for 7 to 14 days, Severe/Complicated : 750 mg twice daily for 7 to 14 days; Acute Sinusitis : 500 mg twice daily for 10 days; Skin and Skin Structure infection: Mild/Moderate : 500 mg twice daily for 7 to 14 days, Severe/Complicated : 750 mg twice daily for 7 to 14 days, Bone and joint infection: Mild/Moderate 500 mg twice daily for 4 to 6 weeks, Severe/Complicated : 750 mg twice daily for 4 to 6 weeks, Intra Abdominal Infection: 500 mg twice daily for 7 to 14 days, Infectious Diarrhea: Mild/Moderate/Severe: 500 mg twice daily for 5 to 7 days, Typhoid Fever : 500 mg twice daily for 10 days, Urethral & Cervical Gonococcal Infections: Uncomplicated: 250 mg Single dose.

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For IV infusion :
Urinary Tract Infection: Mild to Moderate: 200 mg 12 hourly for 7-14 days;Severe or Complicated: 400 mg 12 hourly for 7-14 days; Lower Respiratory Tract infection: Mild to Moderate: 400 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 8 hourly for 7-14 days; Nosocomial Pneumonia: Mild/Moderate/Severe: 400 mg 8 hourly for 10-14 days; Skin and Skin Structure: Mild to Moderate: 400 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 8 hourly for 7-14 days; Bone and Joint Infection: Mild to Moderate: 400 mg 12 hourly for more than 4-6 weeks; Severe/Comlicated: 400 mg 8 hourly for more than 4-6weeks; Intra abdominal (Acute abdomen): Complicated: 400 mg 12 hourly for 7-14 days; Acute Sinusitis: Mild/Moderate: 400 mg 12 hourly for10 days: Chronic Bacterial Prostatitis: Mild/Moderate: 400 mg 12 hourly for 28 Days.

Children and adolescents:
RTI & GI infections: Neonate-15mg/kg twice daily, Child (1 month -18 years)-20mg/kg (max 750 mg) twice daily; UTI: Neonate-10 mg/kg twice daily, Child (1 month -18 years)-10mg/kg (max 750 mg) twice daily; Pseudomonal lower respiratory tract infection in cystic fibrosis: Child (1 month -18 years) – 20mg/kg (max 750 mg) twice daily; Anthrax (treatment & post exposure prophylaxis): Child (1 month -18 years) – 20mg/kg (max 750 mg) twice daily.
Use in Pregnancy and Lactation
Reproduction studies performed in rats and rabbits using parenteral and oral administration did not reveal any evidence of teratogenicity, impairment of fertility or impairment of pre or postnatal development. However, as with other quinolones, Ciprofloxacin has been shown to cause arthropathy in immature animals and therefore, its use during pregnancy is not recommended. Studies in rats have indicated that Ciprofloxacin is secreted in milk, administration to nursing mothers is thus not recommended.

Side Effects

Ciprofloxacin is generally well tolerated. Frequent adverse reactions are- Gastrointestinal disturbance: e.g. nausea diarrhea, vomiting, dyspepsia, abdominal pain. Disturbance of the CNS: e.g. dizziness, headache, tiredness, confusion, convulsions. Hypersensitivity reactions: e.g. skin rashes, pruritus, and possible systemic reactions. Other possible side effects are – joint pain, light sensitivity, transient increase in liver enzyme (especially in patients with history of liver damage), serum bilirubin, urea or serum creatinine. Arthralgia and myalgia may also occur.

Precautions

Ciprofloxacin should be used with caution in patients with a history of convulsive disorders. Crystalluria related to the use of Ciprofloxacin has been observed only rarely. Patients receiving Ciprofloxacin should be well hydrated to avoid excessive alkalinity of the urine.

Beuflox Injection should only be administered by slow intravenous infusion over a period of 60 minutes. Local IV site reactions have been reported with the intravenous administration of Ciprofloxacin. These reactions are more frequent if infusion time is 30 minutes or less or if small vein of the hand are used.

Use in Pregnancy & Lactation

Reproduction studies performed in rats and rabbits using parenteral and oral administration did not reveal any evidence of teratogenicity, impairment of fertility or impairment of pre or postnatal development. However, as with other quinolones, Ciprofloxacin has been shown to cause arthropathy in immature animals and therefore, its use during pregnancy is not recommended. Studies in rats have indicated that Ciprofloxacin is secreted in milk, administration to nursing mothers is thus not recommended.

Drug Interaction

Concurrent administration of Ciprofloxacin with theophylline may lead to elevated plasma concentrations of theophylline. Plasma level of theophylline should be monitored and dosage adjustments made as appropriate. Antacid containing magnesium hydroxide or aluminium hydroxide may interfere with the absorption of Ciprofloxacin & concurrent administration of these agents with Ciprofloxacin should be avoided. Probenecid interferes with renal tubular secretion of Ciprofloxacin and produces an increase in the level of Ciprofloxacin in the serum. As with other broad spectrum antibiotics prolonged use of Ciprofloxacin may result in over growth of non-susceptible organisms. Repeated evaluation of patient’s conditions and microbial susceptibility testing is essential. If superinfections occur during therapy, appropriate measure should be taken.

Over Dose

In case of acute overdose, the patient should be carefully observed and given supporative treatment, including monitoring of renal function. Adequate hydration must be maintained.

Commercial Pack

Beuflox 250: Box containing 6 blister strips of 3 film coated tablet.
Beuflox 500: Box containing 2 blister strips of 10 film coated tablet.
Beuflox 750: Box containing 2 blister strips of 10 film coated tablet.
Beuflox 250 granules for suspension: Each box contains 14 sachets.
Beuflox 125 granules for suspension: Each box contains 14 sachets.
Beuflox Granules for suspension 60 ml: Each glass bottle contains Granules for preparing 60 ml suspension.
Beuflox IV Infusion 100 ml: Each box contains 1 bag of 100 ml solution for injection.

Others

Information for patients: Beuflox should be swallowed whole with an adequate amount of liquid, it may be taken with or without meals. The preferred time of dosing is two hours after a meal and patients should not take antacid within two hours of dosing.

Directions for use of granules for suspension
Whole contents of the packet should be taken into a small glass containing 2-3 teaspoonful of water. Other liquids or foods should not be used. The mixer should be stirred well and drink immediately. The glass should be refilled with water and drink.
Direction for reconstitution of suspension (60 ml)
Shake the bottle well to loosen the granules. Add 50 ml (with the help of supplied measuring cup) of boiled cool water to the dry granules in the bottle. Shake the bottle vigorously until all the granules is in suspension.

FAQ:

  1. What Ciprofloxacin is used for?

Answer : About ciprofloxacin

It belongs to a group of antibiotics called fluoroquinolones. It is used to treat serious infections, or infections when other anitbiotics have not worked. It’s used to treat bacterial infections, such as: chest infections (including pneumonia)

 

  1. Is ciprofloxacin a strong antibiotic?

Answer :  Is ciprofloxacin (Cipro) a strong antibiotic? Ciprofloxacin (Cipro) works against a lot of different bacteria and treats quite a few types of infections. There are other antibiotics that can treat more types of infections, or more serious infections. “Stronger” antibiotics are not always the best choice, though.

 

  1. What is the side effect of ciprofloxacin?

Answer :  Nausea, diarrhea, dizziness, lightheadedness, headache, and trouble sleeping may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

 

  1. What foods should I avoid while taking Cipro?

Answer :  Do not take ciprofloxacin with dairy products such as milk or yogurt, or with calcium-fortified juice. You may eat or drink these products with your meals, but do not use them alone when taking ciprofloxacin. Antibiotic medicines can cause diarrhea, which may be a sign of a new infection.

 

  1. Will 3 days of Cipro cure UTI?

Answer :   Conclusions: Ciprofloxacin at a dosage of 100 mg BID for 3 days was the minimum effective dose for the treatment of uncomplicated urinary tract infection in women.

 

  1. H ow many days should I take ciprofloxacin 500mg?

Answer :   Adults—250 to 500 milligrams (mg) 2 times a day, taken every 12 hours for 7 to 14 days. Children—Dose is based on body weight and must be determined by your doctor. The dose is usually 10 to 20 milligrams (mg) per kilogram (kg) of body weight every 12 hours for 10 to 21 days.

 

  1. What is best antibiotic for urinary tract infection?

Answer :   Trimethoprim/sulfamethoxazole, nitrofurantoin, and fosfomycin are the most preferred antibiotics for treating a UTI.

 

  1. Does ciprofloxacin make you pee a lot?

Answer :   This medication may rarely cause serious changes in blood sugar levels, especially if you have diabetes. Watch for symptoms of high blood sugar including increased thirst and urination. Ciprofloxacin may increase the blood sugar-lowering effects of the medication glyburide.

 

  1. Is ciprofloxacin a penicillin?

Answer :   Amoxicillin and Cipro belong to different antibiotic drug classes. Amoxicillin is a penicillin-type antibiotic and Cipro is a fluoroquinolone antibiotic. Side effects of amoxicillin and Cipro that are similar include diarrhea, abdominal pain, nausea, vomiting, and rash.

 

  1. Is Cipro good for urinary tract infection?

Answer :  Cipro is effective for treating infections caused by many different types of bacteria. These include bacteria that cause infections in the urinary tract, abdomen, skin, prostate, and bone, as well as other types of infections.

 

  1. Does ciprofloxacin turn your pee orange?

Answer :   Your urine will turn orange while you are taking this medication, and this may cause your clothing to become stained. If you notice any kidney problems symptoms of shortness of breath, or confusion, contact your physician or healthcare provider immediately.

 

  1. What should I eat while taking Cipro?

Answer :  You may eat or drink dairy products or calcium-fortified foods with a regular meal, but do not use them alone when taking ciprofloxacin. They could make the medication less effective. When ciprofloxacin tablets are given with enteral (tube) feedings, ciprofloxacin may not work as well.

  1. Is Cipro bad for your heart?

Answer :  In a study published today in the Journal of the American College of Cardiology, researchers at the University of British Columbia (UBC) in partnership with the Provincial Health Services Authority’s (PHSA) Therapeutic Evaluation Unit found that current users of fluoroquinolone antibiotics, such as Ciprofloxacin or

 

  1. How long does it take for Cipro to work?

Answer :  You should begin to notice some easing of your symptoms a few days after you start taking ciprofloxacin. However, it may be a week or more before you get the full benefit of this drug. If you don’t feel better or your symptoms get worse, tell your doctor.

 

  1. What pain reliever can I take with ciprofloxacin?

Answer :  Painkillers. It’s fine to take paracetamol and co-codamol with ciprofloxacin. You should avoid taking anti-inflammatory medicines such as aspirin, ibuprofen or naproxen unless these have been prescribed by your doctor or recommended by your pharmacist.

 

  1. Is ciprofloxacin stronger than amoxicillin?

Answer :  A recent report in the Journal of the American Medical Association has shown that ciprofloxacin (Cipro) more effectively treats bladder infections than amoxicillin-clavulanate (Augmentin). Researchers randomly assigned 370 women with cystitis to receive a 3-day course of either Cipro or Augmentin.

 

  1. Why won’t my UTI go away even with antibiotics?

Answer :  Sometimes, persistent UTI-like symptoms may indicate another issue, such as antibiotic resistance, improper treatment, or an underlying condition. It’s always important to reach out to your doctor if you’re concerned about UTI symptoms that don’t resolve with antibiotic treatment.

 

  1. What is the fastest way to get rid of a bladder infection?

Answer :  Most bladder infections are treated with antibiotics. This is the fastest way to get rid of a bladder infection.

Medications to treat bladder infections include:

  1. Nitrofurantoin (Macrobid)
  2. Trimethoprim-sulfamethoxazole (Bactrim)
  3. Fosfomycin (Monurol)

 

  1. Can ciprofloxacin treat Covid?

Answer :  Ciprofloxacin can be safely taken at higher oral doses (above 500 mg twice a day) as a long-term therapy and thus different dosage options can be considered [30]. Therefore, the possible dual-mode of action could be especially used in the broad range of anti-infective activities in patients with COVID-19.

 

  1. Can I take ibuprofen with ciprofloxacin?

Answer :  In particular, do not take painkillers called non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, while you are taking ciprofloxacin.

 

 

  1. Is Cipro good for kidney infection?

Answer :  This medication is used to treat kidney or bladder (urinary tract) infections. Ciprofloxacin belongs to a class of drugs called quinolone antibiotics. It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections.

 

  1. Does cranberry juice help a UTI?

Answer :  Cranberries. Cranberry juice or cranberries don’t treat a UTI once it’s started. However, a chemical in cranberries may help prevent certain types of bacteria that can cause a bacterial UTI from attaching to the lining of your bladder. This may be helpful in preventing future UTIs.

 

  1. Are bananas good for urinary tract infection?

Answer :  Bananas and other high-fiber foods can be good for urinary tract health and preventing urinary tract infections by encouraging regular bowel movements and relieving pressure on urine flow.

 

  1. How long does Cipro take to cure UTI?

Answer :  Some common antibiotics used for treating UTIs include nitrofurantoin (Macrobid), sulfamethoxazole/trimethoprim (Bactrim), and ciprofloxacin (Cipro). Typically, you only need to take them for 3 to 5 days, and most people start to feel relief within the first 2 to 3 days.

 

  1. Can you lay down after taking ciprofloxacin?

Answer :  Do not lie down immediately after taking medicine, to make sure the pills have gone through the esophagus into the stomach. Notify your healthcare provider if you experience painful swallowing or feel that the medicine is sticking in your throat.

 

  1. Who should not take ciprofloxacin?

Answer :  Ciprofloxacin should not normally be given to children younger than 18 years of age unless they have certain serious infections that cannot be treated with other antibiotics or they have been exposed to plague or anthrax in the air.

 

  1. What is a good alternative to ciprofloxacin?

Answer :   Alternatives for Cipro

  • fosfomycin trometamol.
  • pivmecillinam (not available in the U.S.)

 

  1. Is Cipro good for strep throat?

Answer :  Cipro (ciprofloxacin) is a good, cheap antibiotic that treats many types of bacterial infections, but it interacts with some food and drugs. Compared to alternatives, Penicillin VK (penicillin) is the preferred choice for treating strep throat infections. This medicine is available as a generic, which is cheap.

 

  1. What is the safest antibiotic?

 

Answer :  Penicillins are the oldest of the antibiotics and are generally safe (but they can cause side effects such as diarrhea, skin rash, fever and more). FQs are the newest group of antibiotics.

 

  1. What can mimic a urinary tract infection?

Answer :  Sexually transmitted infections (gonorrhea, chlamydia, and mycoplasma) cause symptoms also common in UTIs, such as painful urination and discharge. Vaginitis, caused by bacteria or yeast, can result in a burning sensation when urinating and similar discomfort that may mimic a UTI.

 

  1. Why do I have UTI symptoms but no infection?

Answer :  It’s also possible that the symptoms may not be caused by a bladder infection, but instead may be caused by an infection in the urethra, the tube that allows urine to pass out of the body. Or, inflammation in the urethra might be causing the symptoms, rather than bacteria.

 

  1. How long can a UTI go untreated?

Answer :  How long does a UTI last untreated? Some UTIs will go away on their own in as little as 1 week. However, UTIs that do not go away on their own will only get worse over time. If you think you have a UTI, speak with a doctor about the best course of action.

 

  1. Can I take vitamin C while taking ciprofloxacin?

Answer :  No interactions were found between ciprofloxacin and Vitamin C. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

 

  1. Can I eat eggs while taking antibiotics?

Answer :  They’re also rich in another digestion-critical bacteria called Bifidobacteria. Foods High in Vitamin K — Antibiotic treatment can rarely lead to Vitamin K deficiency which may contribute to bacteria imbalances. Get more K by ingesting leafy green vegetables, cauliflower, liver, and eggs.

 

  1. What is Cephalexin 500 mg used for?

Answer :  Cephalexin is used to treat certain infections caused by bacteria such as pneumonia and other respiratory tract infections; and infections of the bone, skin, ears, , genital, and urinary tract. Cephalexin is in a class of medications called cephalosporin antibiotics. It works by killing bacteria.

 

  1. Can I take Cipro on an empty stomach?

Answer :  Ciprofloxacin is best taken on an empty stomach, swallowed whole with a glass of water. Your doctor will prescribe a dose and regime that is appropriate for your condition.

 

  1. Why would a doctor prescribe ciprofloxacin?

Answer :   About ciprofloxacin

It is used to treat serious infections, or infections when other anitbiotics have not worked. It’s used to treat bacterial infections, such as: chest infections (including pneumonia) skin and bone infections.

 

  1. Is ciprofloxacin a strong antibiotic?

Answer :  Is ciprofloxacin (Cipro) a strong antibiotic? Ciprofloxacin (Cipro) works against a lot of different bacteria and treats quite a few types of infections. There are other antibiotics that can treat more types of infections, or more serious infections. “Stronger” antibiotics are not always the best choice, though.

 

  1. Is ciprofloxacin stronger than penicillin?

Answer :  Ciprofloxacin was superior to penicillin V; there were fewer resistant strains (one compared to 11), and the eradication rate (57% compared to 43%) as well as the clinical efficacy (60% compared to 48%) of ciprofloxacin were better than those of penicillin V–even in a daily dose of 6.0 g.

 

  1. How do you tell if a UTI has spread to your kidneys?

Answer :  Signs and symptoms of a kidney infection might include:

  • Back, side (flank) or groin pain.
  • Abdominal pain.
  • Frequent urination.
  • Strong, persistent urge to urinate.
  • Burning sensation or pain when urinating.
  • Nausea and vomiting.

 

 

  1. What happens if my urinary tract infection doesn’t go away?

Answer :  If you don’t treat a UTI, a long-lasting kidney infection can hurt your kidneys forever. It can affect the way your kidneys function and lead to kidney scars, high blood pressure, and other issues. Sometimes it can even be life-threatening. You’ll take antibiotics to treat a kidney infection.

 

  1. When do you know a UTI is gone?

Answer :  If your doctor confirms that you have a simple UTI, expect symptoms to disappear within 3-10 days. If your doctor says your UTI is more severe, it may take several weeks for the infection to clear and your symptoms to disappear.

 

  1. What is the most common cause of bladder infection?

Answer :  According to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) , most bladder infections are caused by Escherichia coli (E. coli). This type of bacteria is naturally present in the large intestines. An infection can occur when bacteria from the stool get onto the skin and enter the urethra.

 

  1. What is the difference between a bladder infection and a urinary tract infection?

Answer :  A UTI is defined as an infection in one or more places in the urinary tract—the ureters, kidneys, urethra, and/or bladder. A bladder infection is just a UTI that’s located in the bladder.

 

  1. Is Cipro good for urinary tract infection?

Answer :  Cipro is effective for treating infections caused by many different types of bacteria. These include bacteria that cause infections in the urinary tract, abdomen, skin, prostate, and bone, as well as other types of infections.

 

  1. What are the most common side effects of ciprofloxacin?

Answer :  Ciprofloxacin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • stomach pain.
  • vaginal itching and/or discharge.
  • pale skin.
  • unusual tiredness.

 

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