World best selling no 1 : A-Mycin (Erythromycin)

Therapeutic Group : Antibiotic

Erythromycin is a macrolide antibiotic, which may be bactericidal or bacteriostatic. Erythromycin binds to the 50S ribosomal subunit of susceptible bacteria and suppresses protein synthesis without affecting nucleic acid synthesis. A-Mycin (Erythromycin) is usually active against following organisms: Gram positive: Staphylococcus aureus, Streptococcus Pyogenes, S. pneumoniae, Corynebacterium diphtheriae, C. minutissimum. Gram-negative: Moraxella catarrhalis, Neisseria gonorrhoeae, Legionella pneumophila, Bordetella pertussis. Mycoplasma: Mycoplasma pneumoniae, Ureoplasma urealyticum. Others: Chlamydia trachomatis, Entamoeba histolytica, Treponema pallidum, Listeria monocytogenes.

A-Mycin Powder for Suspension: After reconstitution each 5 ml suspension contains Erythromycin Ethylsuccinate USP equivalent to 125 mg of Erythromycin..
A-Mycin Paediatric Drops: After reconstitution each 5 ml suspension contains Erythromycin Ethylsuccinate USP equivalent to 200 mg of Erythromycin.
A-Mycin is highly effective in the treatment of a wide variety of clinical infections, such as
1.Upper respiratory tract infections: Tonsillitis, peritonsillar abscess, pharyngitis, laryngitis, sinusitis, and secondary infections in cold and influenza.
2.Lower respiratory tract infections: Tracheitis, acute and chronic bronchitis. Mycoplasma pneumoniae (lobar pneumonia, broncho pneumonia, primary atypical pneumoniae), bronchiectasis.
3.Skin and soft tissue infections: Boils and carbuncles, paronychia, abscesses, pustular acne, impetigo, cellulitis, furuncolosis, erythrasma.
4.Veneral infections: Non-specific urethritis, syphilis (if the patient is allergic to penicillin).
5.Gastro-intestinal infections: Cholecystitis, Staphylococcal enterocolitis, infectious diarrhoea, & cholera.
6.Ear and oral infections: 0titis media and otitis externa, gingivitis, dental abscesses.
7.Prophylaxis: Pre-operative and post-operative, trauma, burns, rheumatic fever.
8.Other infections: Diphtheria, whooping cough.

Dosage & Administration:

Adults: Usually 250 mg every 6 hours, or 500 mg every 12 hours. May increase up to 4 g/day, according to severity of infection.

Infections Dosage and Administration
Upper respiratory tract infections of mild to moderate severity 250 to 500 mg 4 times a day for 10 days
Lower respiratory infections of mild to moderate severity 250 to 500 mg 4 times a day for 10 days
Respiratory tract infections due to Mycoplasma pneumoniae 500 mg 6 hours for 5 to 10 days, treat severe infections for up to 3 weeks
Skin and soft tissue infections of mild to moderate severity 250 to 500 mg 4 times a day for 10 days
Pelvic inflammatory diseases (PID), acute due to Neisseria gonorrhoeae 500 mg 4 times a day for 10 to 14 days
Urogenital infection during pregnancy caused by Chlamydia trachomatis 500 mg 4 times daily for 7 days or
250 mg 4 times daily for 14 days
Urethral, endocervical or rectal infections, uncomplicated 500 mg 4 times daily for 7 days or
250 mg 4 times daily for 14 days
Non-gonococcal urethritis 500 mg 4 times daily for at least 7 days
Neisseria gonorrhoeae: Uncomplicated urethral, endocervical or rectal infections and in penicillinase producing N. gonorrhoeae(PPNG) 500 mg 4 times a day for 7 days
Early syphillis (primary, secondary or latent syphillis of < 1 year duration) 500 mg 4 times a day for 14 days
Severe or chronic diarrhoea 500 mg 4 times a day for 7 days
Rheumatic fever 250 mg 2 times daily
Bacterial endocarditis 1 g 2 hours prior to procedures, then 500 mg 6 hours after initial dose
Acne 500 mg twice daily for 3 months reduced to 250 mg twice for 3 months

Children:
The usual oral dose is 30-50 mg/kg body weight per day in divided doses. For more severe infections, the dose may be doubled.

Erythromycin is contraindicated in patients with known hypersensitivity of this antibiotic.
Erythromycin should be used with care in patients with existing hepatic impairment. It has been suggested that Erythromycin should be used with care in patients with history of arrhythmia.
Gastro-intestinal: Abdominal cramp & discomfort, nausea, vomiting & diarrhoea. Hypersensitivity reaction may also be responsible for the hepatotoxicity sometimes in patients receiving Erythromycin or its derivatives.
A-Mycin (Erythromycin) may decrease the clearance of theophylline causing increased theophylline serum level and potential toxicity. It may decrease the metabolism of carbamazepine, triazolam, hexobarbital and phenytoin causing increased serum levels and potential toxicity. A-Mycin (Erythromycin) may decrease the clearance of warfarin and thus potentiate the hypoprothrombinic effect of warfarin.

Use in special groups:

Use in pregnancy: A-Mycin (Erythromycin) crosses the placenta. Fetal plasma concentrations are variously stated to the 5 to 20% of these in the mother.
Use in lactation: It is readily excreted in breast milk.

A-Mycin Powder for Suspension: Bottle containing dry powder for reconstitution of 100 ml suspension.
A-Mycin Paediatric Drops: Bottle containing dry powder for reconstitution of 60 ml suspension with dropper.

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FAQ:

1.What is erythromycin commonly used for?

Answer : Erythromycin is an antibiotic. It’s widely used to treat chest infections, such as pneumonia, skin problems, such as acne and rosacea, dental abscesses, and sexually transmitted infections

 

2.Is azithromycin same as erythromycin?

Answer :  Azithromycin is similar to erythromycin in structure but does not have significant drug-drug interactions as seen with erythromycin. Purpose: This study aims to determine whether azithromycin stimulates antral activity in patients with chronic gastrointestinal pain and refractory gastroparesis.

 

3. Is erythromycin a penicillin?

Answer :  Erythromycin is an antibiotic. It can be taken by people who are allergic to penicillin. Space your doses out evenly over the day and complete the full course of this antibiotic, even if you feel your infection has cleared up. The most common side-effects are feeling sick (nausea) and tummy (abdominal) discomfort.

 

4. Can erythromycin cure sore throat?

Answer :  Erythromycin is used to treat: Streptococcal infections of the throat (“strep throat”) and skin. Lung infections, for example, pneumonia caused by streptococcal pneumoniae, mycoplasma pneumoniae, and legionella pneumophila (legionnaires disease)

 

5. What bacteria does erythromycin treat?

Answer :  Erythromycin can be used to treat bacteria responsible for causing infections of the skin and upper respiratory tract, including Streptococcus, Staphylococcus, Haemophilus and Corynebacterium genera.

 

6. What can you not take with erythromycin?

Answer :  Many drugs besides erythromycin may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, cisapride, pimozide, procainamide, propafenone, quinidine, sotalol, among others. Other medications can affect the removal of erythromycin from your body, which may affect how erythromycin works.

 

7. Is azithromycin stronger than erythromycin?

Answer :  CONCLUSIONS. In this large, multicenter, randomized trial, we found that azithromycin is as effective as and better tolerated than erythromycin estolate for the treatment of pertussis in children.

 

8. Is amoxicillin better than erythromycin?

Answer :  Conclusion: The available data suggest that amoxicillin is more effective than erythromycin for the treatment of antenatal C trachomatis infection and has fewer gastrointestinal side effects, leading to better compliance.

 

9. Can I take azithromycin for throat pain?

Answer :  Azithromycin is an antibiotic. It’s widely used to treat chest infections such as pneumonia, infections of the nose and throat such as sinus infection (sinusitis), skin infections, Lyme disease, and some sexually transmitted infections.

 

10. Can erythromycin treat cough?

Answer :  Erythromycin is used to treat certain infections caused by bacteria, such as infections of the respiratory tract, including bronchitis, pneumonia, Legionnaires’ disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing); diphtheria (a serious infection in the

 

11. Can you take paracetamol with erythromycin?

Answer :  If you need to ease pain or lower a high temperature (fever), it’s fine to take paracetamol or ibuprofen with erythromycin. Erythromycin doesn’t affect hormonal contraceptives such as the pill.

 

12. Who can prescribe erythromycin?

Answer : Erythromycin is available only with your doctor’s prescription. This product is available in the following dosage forms: Ointment.

 

13. Is erythromycin good for itchy throat?

 

Answer :  Penicillin is the most common antibiotic prescribed for strep throat. If you have a penicillin allergy, your doctor may prescribe erythromycin. Your doctor most likely will give you a 10-day supply. It is critical that you take all of the medication even if your symptoms subside or go away.

 

14. Which is best medicine for throat infection?

What is the best medicine for a sore throat?

Answer :

Best medications for a sore throat
Chloraseptic (phenol) Anesthetic Numbs throat
Penicillin V Antibiotic Kills bacteria causing sore throat
Amoxicillin Antibiotic Kills bacteria causing sore throat
Cephalexin (Keflex) Antibiotic Kills bacteria causing sore throat

 

15. What is the tablet for throat infection?

Answer : Doctors most often prescribe penicillin or amoxicillin (Amoxil) to treat strep throat. They are the top choices because they’re safer, inexpensive, and they work well on strep bacteria.

 

16.How many days should I take erythromycin?

Answer :  Your doctor will advise you on how long to take erythromycin for (usually 5 to 10 days), but depending on the infection, it could be longer. Always take your erythromycin exactly as your doctor has told you.

 

17. Why is erythromycin not used?

Answer :  As erythromycin may cause serious rashes in a small number of patients, anyone who has experienced similar symptoms in the past should avoid future use of the drug. Pregnant women should avoid using erythromycin estolate as it may precipitate hepatotoxicity.

 

18. What part of the cell does erythromycin target?

Answer :  Erythromycin is a broad-spectrum, macrolide antibiotic with antibacterial activity. Erythromycin diffuses through the bacterial cell membrane and reversibly binds to the 50S subunit of the bacterial ribosome. This prevents bacterial protein synthesis.

 

19.What happens if you take erythromycin on an empty stomach?

Answer :  Food decreases the levels of erythromycin in your body. Take erythromycin on an empty stomach at least 30 minutes before or 2 hours after a meal. This will make it easier for your body to absorb the medication. However, some erythromycin products may be taken without regard to meals.

 

20. Can erythromycin make you feel hungry?

Answer :  The motilin agonist, erythromycin, induces gastric phase III of the migrating motor complex, which in turn generates hunger peaks.

 

21. Can you drink milk when you take antibiotics?

Answer :  It’s recommended that dairy products such as cheese, milk, butter, and yogurt should not be consumed until 3 hours after a dose of antibiotics is taken. Likewise, juices or supplements containing calcium may also reduce effectiveness.

 

22. Why is azithromycin given in Covid?

Answer :  The antiviral and anti-inflammatory properties of azithromycin are suited to patients with early stage COVID-19.

 

23. Which is better for throat infection erythromycin or azithromycin?

Answer :  Ery-Tab (Erythromycin) works well to treat a variety of bacterial infections, but check for drug interactions before taking it. Treats bacterial infections. Zithromax (azithromycin) is good for treating many bacterial infections and is available in generic form.

 

24. Can you take erythromycin and azithromycin together?

Answer :  erythromycin azithromycin

Using erythromycin together with azithromycin can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect.

 

24. What is erythromycin 500mg for?

Answer : Erythromycin is used to prevent and treat infections in many different parts of the body, including respiratory tract infections, skin infections, diphtheria, intestinal amebiasis, acute pelvic inflammatory disease, Legionnaire’s disease, pertussis, and syphilis.

 

25. What is the strongest antibiotic for bacterial infection?

Answer :  The world’s last line of defense against disease-causing bacteria just got a new warrior: vancomycin 3.0. Its predecessor—vancomycin 1.0—has been used since 1958 to combat dangerous infections like methicillin-resistant Staphylococcus aureus.

 

26. Can I take amoxicillin and erythromycin together?

Answer :  This study showed that combining amoxicillin and erythromycin could give beneficial chemotherapeutic outcomes because the resultant synergistic effect surpasses their individual performances. This synergistic effect may easily help in understanding if there are therapeutic efficacies or failure in treatment situation.

 

26. Is Azithral 500 good for throat infection?

Answer :  Azithral 500 tablet is used for the treatment of bacterial infection in the ears, lungs, throat, tonsils, airways, nasal passage, skin and soft tissue. It is also used for the treatment of enteric fever and pneumonia or lung infection due to coming in contact with an infected person (CAP)..

 

27. Is azithromycin good for dry cough?

Answer :  Looking at subgroups of responders, there was a large and significant improvement in LCQ score in patients with chronic cough and a concurrent diagnosis of asthma who were treated with azithromycin (mean, 6.19; 95% CI, 4.06 to 8.32).

 

28. Can azithromycin treat cough?

Answer :  The macrolide, azithromycin, is a potentially attractive option for treating patients with a chronic wet cough. It is well-tolerated, has good oral bioavailability and a prolonged half-life allowing convenient once-daily or even one-to three times weekly dosing (4).

 

29. How do I know if my cough is viral or bacterial?

Answer :  In addition to lab tests, sputum or mucus from a cough can be visually examined to determine whether bronchitis is viral, bacterial, or both. Clear or white mucus often indicates a viral infection, while yellow or green mucus may suggest a bacterial infection.

 

30. What is the strongest antibiotic for upper respiratory infection?

Answer :  Amoxicillin is the preferred treatment in patients with acute bacterial rhinosinusitis. Short-course antibiotic therapy (median of five days’ duration) is as effective as longer-course treatment (median of 10 days’ duration) in patients with acute, uncomplicated bacterial rhinosinusitis.

 

31. What is the best antibiotic for a chest infection?

Answer :  Other appropriate antibiotics may include the fluoroquinolone antibiotics such as levofloxacin (Levaquin); or combined therapy of a beta-lactam such as amoxicillin or amoxicillin/clavulanate (Augmentin) with a macrolide antibiotic.

 

32. Can erythromycin make you feel tired?

Answer :  dizziness, headache, feeling tired, vaginal itching or discharge, or.

 

33. What will happen if I take 4 paracetamol?

Answer :  Taking 1 or 2 extra tablets by accident is unlikely to be harmful, as long as you do not take more than 8 tablets in 24 hours. Wait at least 24 hours before taking any more paracetamol.

 

34. What painkillers can I take with antibiotics?

Answer :  Yes! It is safe to use paracetamol at the same time as taking most antibiotics. Taking antibiotics at the same time as paracetamol shouldn’t cause any problems.

 

35. Does erythromycin treat fungal infections?

Answer :  Erythromycin ophthalmic will not treat a viral or fungal eye infection.

 

36. What is the brand name of erythromycin?

Answer :  Erythromycin – Brand names and Manufacturer. A/T/S (Medicis Pharmaceutical – U.S.) BENZAMYCIN PAK (Dermik Labs – U.S.) BRISTAMYCIN (BMS – U.S.)

 

36. Does erythromycin help with dry eyes?

Answer :  The patient will use antibiotic ophthalmic drops or ointments, such as erythromycin, azithromycin and bacitracin, among others, for about seven to 10 days to decrease the number of bacteria that break down the lipid layer of the tear film. In ointment form, these also lubricate the eyes overnight.

 

37. What causes a sore throat and cure?

Answer :  The most common cause of a sore throat (pharyngitis) is a viral infection, such as a cold or the flu. A sore throat caused by a virus resolves on its own. Strep throat (streptococcal infection), a less common type of sore throat caused by bacteria, requires treatment with antibiotics to prevent complications.

 

38. Can I take erythromycin for tonsillitis?

Answer :  Our results suggest that twice-a-day regimen of erythromycin base is an effective and well-tolerated treatment of streptococcal tonsillitis.

 

39. How do you get throat infections?

Answer :  8 causes of sore throats

  1. Colds, the flu, and other viral infections. Viruses cause about 90 percent of sore throats ( 2 ). …
  2. Strep throat and other bacterial infections. …
  3. Dry air. …
  4. Smoke, chemicals, and other irritants. …
  5. Gastroesophageal reflux disease (GERD) …

 

40.Is Vitamin C good for a sore throat?

Answer :  A review of 21 controlled trials using 1 to 8 grams of vitamin C per day found that “in each of the twenty-one studies, vitamin C reduced the duration of episodes and the severity of the symptoms of the common cold by an average of 23%.” The optimum amount of vitamin C to take for cold treatment remains in debate but …

 

41. What are the signs of a bacterial throat infection?

Answer :  Symptoms of bacterial pharyngitis may include :

  • significant pain when swallowing.
  • tender, swollen neck lymph nodes.
  • visible white patches or pus on the back of the throat.
  • tonsils that are swollen and red.
  • a headache.
  • abdominal pain.

 

42. What is the fastest way to cure a throat infection?

Answer :  16 Best Sore Throat Remedies to Make You Feel Better Fast, According to Doctors

  1. Gargle with salt water—but steer clear of apple cider vinegar. …
  2. Drink extra-cold liquids. …
  3. Suck on an ice pop. …
  4. Fight dry air with a humidifier. …
  5. Skip acidic foods. …
  6. Swallow antacids. …
  7. Sip herbal teas. …
  8. Coat and soothe your throat with honey.

 

43. Is Ginger good for sore throat?

Answer :  Not just for the taste, ginger is widely used for its various medicinal benefits. One of the most common and scientifically proven health benefits of ginger is that it can treat sore throat. Ginger helps in soothing a sore throat in two ways – one by relieving the pain and second by fighting the infections.

 

44. Can erythromycin be used for sore throat?

Answer :  What are the uses for erythromycin? Erythromycin is used to treat: Streptococcal infections of the throat (“strep throat”) and skin. Lung infections, for example, pneumonia caused by streptococcal pneumoniae, mycoplasma pneumoniae, and legionella pneumophila (legionnaires disease)

 

45. What are the throat problems?

Answer :  Conditions Treated

  • Heartburn / Gastroesophageal Reflux Disease (GERD)
  • Laryngeal Cancer (cancer of the larynx)
  • Salivary Gland Diseases and Disorders.
  • Sore Throat.
  • Strep Throat.
  • Swallowing Disorders (Dysphagia)
  • Voice Disorders.

 

46. What bacteria does erythromycin treat?

 

Answer :  Erythromycin can be used to treat bacteria responsible for causing infections of the skin and upper respiratory tract, including Streptococcus, Staphylococcus, Haemophilus and Corynebacterium genera.

 

47. Is amoxicillin better than erythromycin?

Answer :  Conclusion: The available data suggest that amoxicillin is more effective than erythromycin for the treatment of antenatal C trachomatis infection and has fewer gastrointestinal side effects, leading to better compliance.

 

 

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