Best Selling No 1 : XfinTM Terbinafine HCL

                                XfinTM

                                                              Terbinafine HCL
                                                  Topical Antifungal (Skin Preparations)

Terbinafine HCL Indication:
Fungal infections of the skin caused by dermatophytes such as Trichophyton rubrum, Trichophyton mentagrophytes, Microsporum canis and Epidermophyton floccosum.
XfinTM Tablet: Onychomycosis of the toenail or fingernail due to dermatophytes, Ringworm (Tinea corporis, Tinea cruris and Tinea pedis) where oral therapy is considered appropriate due to the site, severity or extent of the infection;
XfinTM Cream: Yeast infections of the skin principally caused by the genus Candida (e.g. Candida albicans), Pityriasis (tinea) versicolor due to Pityrosporum orbiculare (also known as Malassezia furfur)

Dosage & Administration:
Tablet:
In each indication, dose of Terbinafine Tablet is 250 mg once daily (duration of treatment varies according to the indication and the severity of infections). In case of onychomycosis, the optimal clinical effect is seen some months after mycological cure and cessation of treatment.
Indications Duration
Onychomycosis (Fingernail) 6 weeks
Onychomycosis (Toenail) 12 weeks
Tinea pedis 2-6 weeks
Tinea corporis 4 weeks
Tinea cruris 2-4 weeks
Cream:
Cream can be applied once or twice daily (duration of treatment varies according to the indication and the severity of infections). Cleanse and dry the affected areas thoroughly before application of Cream. Apply the Cream to the affected skin and surrounding area in thin layer and rub in lightly.
Indications Duration
Tinea pedis 1 week
Tinea corporis, Tinea cruris 1-2 weeks
Cutaneous candidiasis 2 weeks
Pityriasis versicolor 2 weeks

Preparation:
XfinTM Tablet: Each pack contains 12 Tablets (in Alu-Alu blister packaging)
Xfin® Cream: Each pack has an Aluminium tube containing 10 gm cream

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FAQ :

1.What is terbinafine hcl used for?

Answer : Terbinafine belongs to the group of medicines called antifungals. It is used to treat fungus infections of the scalp, body, groin (jock itch), feet (athlete’s foot), fingernails, and toenails.

 

2. What should I avoid while taking terbinafine?

Answer : What should I avoid while taking terbinafine? Avoid coffee, tea, cola, energy drinks or other sources of caffeine while taking terbinafine. Avoid exposure to sunlight or tanning beds. Terbinafine can make you sunburn more easily.

 

3. What are the side effects of terbinafine?

Answer : Terbinafine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • feeling sad, worthless, restless, or other changes in mood.
  • loss of energy or interest in daily activities.
  • changes in how you sleep.

 

4.Is weight gain a side effect of terbinafine?

Answer : swelling, rapid weight gain, little or no urinating; blood in your urine or stools; weight loss due to taste changes or loss of appetite; or. skin sores, butterfly-shaped skin rash on your cheeks and nose (worsens in sunlight).

 

5.What kills toenail fungus instantly?

Answer : The fastest way to eliminate the infection is through toenail laser treatment. Laser nail therapy specifically targets the microorganisms under your nail while leaving the keratin intact. In just a few treatments, the infection can be entirely eliminated.

 

6.How safe is terbinafine 250mg?

Answer : Terbinafine may rarely cause serious (possibly fatal) liver disease. Get medical help right away if you have any symptoms of liver damage, such as: nausea/vomiting that doesn’t stop, loss of appetite, severe stomach/abdominal pain, yellowing eyes/skin, dark urine. A very serious allergic reaction to this drug is rare.

 

7.How do I know if terbinafine is working?

Answer : Terbinafine solution usually starts to work within a few days. Talk to your doctor if your symptoms do not get better within 1 week. The cream, gel or spray usually starts to work within a few days. Talk to your doctor if your symptoms do not get better within 2 weeks.

 

8.What is the best time of day to take terbinafine?

Answer : How to take terbinafine tablets

  • Timing: Take terbinafine tablets at the same time each day, either in the morning OR in the evening. …
  • Missed dose: If you forget to take your dose, take it as soon as you remember that day.

 

9.How fast does terbinafine work on nail fungus?

Answer : Following oral administration, terbinafine is rapidly absorbed and widely distributed to body tissues including the poorly perfused nail matrix. Nail terbinafine concentrations are detected within 1 week after starting therapy and persist for at least 30 weeks after the completion of treatment.

 

10.Why should you avoid caffeine while taking terbinafine?

Answer : The body breaks down caffeine to get rid of it. Terbinafine (Lamisil) can decrease how fast the body gets rid of caffeine. Taking caffeine along with terbinafine (Lamisil) can increase the risk of caffeine side effects including jitteriness, headache, increased heartbeat, and other effects.

 

11.Is terbinafine bad for your liver?

Answer : Some people taking terbinafine have developed severe liver damage leading to liver transplant or death. Call your doctor at once if you have symptoms of liver damage, such as nausea, upper stomach pain, vomiting, loss of appetite, tiredness, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

 

12.What is the safest oral antifungal?

Answer : Fluconazole, and itraconazole are the preferred oral agents. Various dosing regimens have been used. Fluconazole has been offered as a single 150- to 300-mg weekly dose for 2-4 weeks and is the safest oral agent.

 

13.Can I drink coffee while taking terbinafine?

Answer : Avoid caffeine (coffee, soda, chocolate) while you are using this medicine. Terbinafine may cause caffeine to stay in your body longer than usual.

 

14.Why is Lamisil hard on the liver?

Answer : The antifungal activity of terbinafine is believed to be due to the selective inhibition of fungal squalene epoxidase, which increases squalene to toxic levels, thus killing the fungal cell.

 

15.Does oral terbinafine cause hair loss?

Answer : Serious skin reactions (e.g., Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, exfoliative dermatitis, bullous dermatitis), psoriasiform eruptions or exacerbation of psoriasis, acute generalized exanthematous pustulosis, hair loss, and photosensitivity reactions have also been reported during ..

 

16.How do I know if my toenail fungus is dying?

Answer : Top 5 signs your toenail fungus has gone nuclear

  1. Nail color changes. If your nail turns white and chalky or yellow, it’s not a good sign. …
  2. Nail position changes. If your nail starts to curl downward or upward, it’s time to be concerned. …
  3. Nail texture changes. …
  4. Nail smell changes. …
  5. Nail sensation changes.

 

17.What is the white hard stuff under my toenails?

Answer : Nail psoriasis sometimes causes too much keratin to grow under the nail. This overgrowth is called subungual hyperkeratosis. People with hyperkeratosis may notice a white, chalky substance under the nail. When this occurs in the toenails, the pressure of shoes pushing down on the nails might cause pain.

 

18.What is the strongest fungal nail treatment?

Answer : Best Overall: Lamisil Terbinafine Hydrochloride AntiFungal Cream 1% Prescription orals and topicals are the most effective way to treat toenail fungus,1 but there are products over-the-counter that can also address mild fungal infections

 

19.What happens if you leave toenail fungus untreated?

Answer : If you let a nail fungus infection go for too long, several problems emerge. The infected nail can become misshapen and increasingly separated from your nail bed. Itching and pain are unpleasant side effects; if they’re too severe, you can have trouble wearing shoes or walking.

20. Can I take terbinafine twice a day?

Answer : For tinea pedis or tinea versicolor: Adults—Use two times a day for seven days. Children—Use and dose must be determined by your doctor.

 

21.Do fungal nail tablets work?

Answer : Many nail problems can look like a fungal infection – for example the changes seen in psoriasis, after a bacterial infection or an old injury – however, antifungal tablets will not help them. The right treatment may depend on knowing which fungus is causing the trouble; it can take several weeks to get culture results.

 

22.How long does terbinafine 250 mg stay in your system?

Answer : It is metabolised by the liver with a half life of 17 hours. This is prolonged in patients with liver or kidney impairment.

 

23.Is terbinafine an antibiotic?

Answer : What Is Terbinafine and How Does It Work? Terbinafine is an antifungal antibiotic used to treat infections caused by fungus that affect the fingernails or toenails (onychomycosis). Oral granules are used to treat a fungal infection of scalp hair follicles in children who are at least 4 years old.

 

24.Will my toenail grow back normal after fungus?

Answer : If the infection is deep and you’ve had it for a while, your doctor may want to remove all or part of your nail. A new nail usually grows back, but it might take a year or so. While it’s coming back, your doctor will likely give you a cream or other treatment to put on your nail bed to keep fungus away.

 

25.Is terbinafine the best antifungal?

Answer : Oral terbinafine is more effective for treating fungal nail infections than griseofulvin (Fulvicin; Gris-Peg) and itraconazole (Sporanox), two other antifungal agents used for treating fungal nail infections.

26.Is it OK to put nail polish on a toenail with fungus?

Answer : This creates a more welcoming environment for fungus and other infectious agents to grow. Wearing polish for a few weeks then removing it and going without for a few weeks is recommended to give your nails a chance to breathe and stay healthy. American Academy of Dermatology Association (AAD).

 

27.Does terbinafine hydrochloride treat toenail fungus?

Answer : Terbinafine is an antifungal medication that fights infections caused by fungus. Terbinafine tablets are used to treat infections caused by fungus that affect the fingernails or toenails. Terbinafine oral granules are used to treat a fungal infection of scalp hair follicles in children who are at least 4 years old.

 

28.What does toe fungus look like when it starts?

Answer : Nail fungus can cause the nail to become thick or ragged and appear yellow, green, brown or black. An infected nail may separate from the nail bed. Nail fungus is a common condition that begins as a white or yellow spot under the tip of your fingernail or toenail.

 

29.Can you take vitamins with terbinafine?

Answer : No interactions were found between terbinafine and Vitamin D3. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

 

30.What are 3 side effects of Lamisil?

Answer : The most common side effects of Lamisil include:

  • diarrhea,
  • nausea,
  • gas,
  • stomach pain or upset,
  • rash,
  • headache, and.
  • abnormal liver function tests.

 

31.Can terbinafine cause blood clots?

Answer : Blood clotting problems . When taking Terbinafine tablets, you may develop a blood clotting problem that can sometimes cause death. Tell your doctor, if you get any unexplained bleeding or bruising.

 

32.What is terbinafine 250mg tablets for?

Answer : Terbinafine 250 mg Tablets are indicated in the treatment of ringworm (tinea corporis, tinea cruris and tinea pedis) where oral therapy is considered appropriate due to the site, severity or extent of the infection.

 

33.Can I take Tylenol with terbinafine?

Answer : No interactions were found between terbinafine and Tylenol. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

 

34.Why are antifungal drugs more toxic to humans?

Answer : Because human cell membranes use cholesterol, instead of ergosterol, antifungal drugs that target ergosterol synthesis are selectively toxic (Figure 1).

 

35.Can probiotics clear nail fungus?

Answer : Studies are continuing in regard to toenail fungus which is the same fungus responsible for “athlete’s foot” infections. Taking a proper Probiotic for a 2-3 month period will help “reset” your gut/immune system and allow your own body to fight the fungal infection without the use of drugs or topical medications.

 

36.Is there an antifungal pill?

Answer : Oral antifungal drugs currently in use include itraconazole, fluconazole, ketoconazole and terbinafine. They are reserved for extensive or severe infection for which topical antifungal agents are inappropriate or ineffective, because of high cost, potential side effects and drug interactions.

 

37.Is Lamisil worth taking?

Answer : Lamisil has an average rating of 7.0 out of 10 from a total of 132 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 26% reported a negative effect.

 

38.How do you know if terbinafine is working?

Answer : Terbinafine solution usually starts to work within a few days. Talk to your doctor if your symptoms do not get better within 1 week. The cream, gel or spray usually starts to work within a few days. Talk to your doctor if your symptoms do not get better within 2 weeks.

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