World No 1 best selling : Intamycin(Gentamicin)

Intamycin(Gentamicin)

Intamycin(Gentamicin) Therapeutic Group: Anti Bacterial Presentation Intamycin 20 Injection: Each 2 ml ampoule contains Gentamicin USP 20 mg as Gentamicin Sulfate. Intamycin 80 Injection: Each 2 ml ampoule contains Gentamicin USP 80 mg as Gentamicin Sulfate. Description Intamycin injection contains Gentamicin Sulfate USP which is an aminoglycoside antibiotic. Gentamicin is a proven bactericidal antibiotic active … Read more

Best Selling : I-Penam(Meropenem)

I-Penam(Meropenem)

I-Penam(Meropenem) Therapeutic Group: Anti Bacterial Presentation I-Penam 250 mg IV Injection: Each vial contains Meropenem 250 mg (as Meropenem for Injection USP). I-Penam 500 mg IV Injection: Each vial contains Meropenem 500 mg (as Meropenem for Injection USP). I-Penam 1 gm IV Injection: Each vial contains Meropenem 1 gm (as Meropenem for Injection USP). Description … Read more

Best Selling : FIRMAC PLUS(Erythromycin+Sulphadiazine + Trimethoprim)

FIRMAC PLUS(Erythromycin+Sulphadiazine + Trimethoprim)

FIRMAC PLUS(Erythromycin+Sulphadiazine + Trimethoprim) Therapeutic Group: Anti Bacterial Presentation Firmac Plus: Each gram powder contains Erythromycin Thiocyanate INN 180 mg, Sulfadiazine BP 150 mg and Trimethoprim BP 30 mg. Description The ingredients of Erythromycin, Sulphadiazine and Trimethoprim are antifolate drug that inhibits bacterial protein synthesis, antifolate drugs and able to kill bacteria. The combination has … Read more

Best Selling Antibacterial : Cefaclav(Cefuroxime & Clavulanic Acid) 1

Cefaclav(Cefuroxime & Clavulanic Acid)

Cefaclav(Cefuroxime & Clavulanic Acid) Therapeutic Group: Anti Bacterial Presentation Cefaclav 125: Each film coated tablet contains Cefuroxime 125 mg as Cefuroxime Axetil USP and Clavulanic Acid 31.25 mg as diluted Potassium Clavulanate BP. Cefaclav 250: Each film coated tablet contains Cefuroxime 250 mg as Cefuroxime Axetil USP and Clavulanic Acid 62.5 mg as diluted Potassium … Read more

Clomipramine Hydrochloride | Uses, Side Effects Etc.

Clomipramine Hydrochloride

Clopramin(Clomipramine Hydrochloride) Therapeutic Group: Tricyclic Antidepressant Presentation Clopramin Tablet: Each tablet contains Clomipramine Hydrochloride USP 25 mg. Description Clomipramine Hydrochloride is an original tricyclic antidepressant, a member of the dibenzazepine group of compounds. It is presumed to influence obsessive and compulsive behaviors through it’s effects on serotonergic neuronal transmission. The actual neurochemical mechanism is unknown … Read more

World No 1 Best selling Clonazepam tablet, side effect and more

Presentation Disopan 0.5 : Each tablet contains Clonazepam USP 0.5 mg. Disopan 1 : Each tablet contains Clonazepam USP 1 mg. Disopan 2 : Each tablet contains Clonazepam USP 2 mg. Disopan 1 injection: Each vial contains Clonazepam USP 1 mg in 1 ml solution. Description Chemically, clonazepam is a benzodiazepine derivative. It exhibits several pharmacologic properties, which are characteristics of the benzodiazepine class of drugs. In human it is capable of suppressing the spike and wave discharge in absence seizure (petit mal) and decreasing the frequency, amplitude, duration and spread of discharge in minor motor seizure. Indications Tablet: • Anxiety disorders (Generalized, Phobic & Panic disorders) • Insomnia and sleep disturbances • Labile arterial hypertension • Peri and Post menopausal anxiety (Anxiety in middle aged women) • Burning Mouth Syndrome • Peri and Post menopausal anxiety (Anxiety in middle aged women) • Postoperative anxiety disorder • Post traumatic stress disorder • Anxiety in cancer patient (palliative treatment) • Tension Headache • Restless legs syndrome (RLS) or Wittmaack–Ekbom syndrome • Nocturnal myoclonus • Tourette's syndrome • Bipolar affective disorder • Resistant depression • Drug-induced dyskinesia • Choreiform movement • Fulgurant pain • Trigeminal neuralgia • Epilespsy Injection: • Epilepsy • Status epilepticus • Myoclonic seizure • Typical and atypical absences (Lennox-Gastaut syndrome) • Infantile spasm • Tonic-clonic seizure • Partial seizure • Absence seizure • Focal seizure Dosage & Administration Tablet: Infants and children Initial dose: 0.01 - 0.03 mg/kg/day. Up to 1 year: 0.25 mg daily in divided dose, not to exceed 0.05 mg/kg/days increase gradually to 0.5 - 1 mg. Increment dose: not more than 0.25 - 0.5 mg 1 - 5 years: 0.25 mg daily in divided dose, at intervals of 3 days increase to 1 - 3 mg. Maintenance dose: 0.1 - 0.2 mg/kg/day. 5 - 12 years: 0.5 mg daily in divided dose, Dosing interval: b.i.d. / t.i.d. increase to 3 - 6 mg. Adults and elderly Initial dose: 1 mg daily in divided dose (Elderly 0.5 mg), not to exceed 1.5 mg/day Increment dose: 0.5 - 1 mg at intervals of 3 days Maintenance dose: 4 - 8 mg/day Maximum dose: 20 mg/day should be administered with caution Dosing interval: b.i.d. / t.i.d. Initial dose should be low and increased gradually to a maintenance dose that controls seizure without toxic effects. During discontinuation, the dose should be tapered. Injection: Infants and children: half of a vial (0.5 mg) by slow IV injection or by IV infusion. Adults: 1 vial (1 mg) by slow IV injection or by IV infusion. This dose can be repeated as required (1 - 4 mg are usually sufficient to reverse the status). In adults, the rate of injection must not exceed 0.25 - 0.5 mg per minute (0.5 – 1.0 mL of the prepared solution) and a total dose of 10 mg should not be exceeded. Slow intravenous injection: The contents of the vial must be diluted with 1 mL of water for injection prior to administration so as to avoid local irritation of the veins. The injection solution should be prepared immediately before use. IV injection should be administered slowly with continuous monitoring of EEG, respiration and blood pressure. Intravenous infusion: Clonazepam (the vial) can be diluted for infusion in a ratio of 1 vial (1 mg) to at least 85 mL diluting media. The diluting media can be any of the following: sodium chloride 0.9%; sodium chloride 0.45% + glucose 2.5%; glucose 5% or glucose 10%. These mixtures are stable for 24 hours at room temperature. Infusion bags other than PVC should be used for infusing Clonazepam. If PVC infusion bags are used then the mixture should be infused immediately or within 4 hours. The infusion time should not exceed 8 hours. Do not prepare Clonazepam infusions using sodium bicarbonate solution, as precipitation of the solution may occur. Intramuscular injection: The IM route should be used only in exceptional cases or if IV administration is not feasible. Side Effects Tablet: The most frequently occurring side effects of clonazepam are referable to CNS depression, drowsiness, fatigue, dizziness, muscle hypotonia, co-ordination disturbance, hypersalivation in infants, paradoxical aggression, irritability and mental change. Injection: Some side effects, like: fatigue, muscle weakness, dizziness, somnolence, light-headedness, ataxia, restlessness, hypersalivation in infants, paradoxical aggression, reduced co-ordination may occur with Clonazepam therapy but these effects are transient and generally disappears in the course of the treatment. Respiratory depression may occur in patients with pre-existing airways obstruction, or brain damage, or if other medications which depress respiration have been given. As a rule, this effect can be avoided by careful adjustment of the dose to individual requirements. Precautions Tablet: When used in patients in whom several different types of seizure disorders coexist, clonazepam may increase the incidence or precipitate the onset of generalized tonic-clonic seizures (grand mal). This may require the addition of appropriate anticonvulsants or an increase in their dosages. The concomitant use of valproic acid and clonazepam may produce absence status. Periodic blood counts and liver function tests are advisable during long term therapy with clonazepam. The abrupt withdrawal of clonazepam, particularly in those patients on long-term, high-dose therapy, may precipitate status epilepticus. Therefore when discontinuing clonazepam, gradual withdrawal is essential. Clonazepam may produce an increase in salivation. This should be considered before giving the drug to patients who have difficulty handling secretions. Because of this and the possibility of respiratory depression, clonazepam should be used with caution in patients with chronic respiratory diseases. Because of the possibility that adverse effects on physical or mental development could become apparent only after many years, a benefit-risk consideration of the long-term use of clonazepam is important in pediatric patients. Injection: The concomitant use of Clonazepam with alcohol and CNS depressants should be avoided. Such concomitant use has the potential to increase the clinical effects of Clonazepam, such as: severe sedation, respiratory and cardiac depression. In some cases, dose adjustment of other medications is necessary. Clonazepam may produce an increase in salivation. This should be considered before giving the drug to patients who have difficulty handling secretions. Clonazepam is adviced to use with caution in patients with chronic respiratory diseases. Because of the possibility that adverse effects on physical or mental development could become apparent only after many years, a benefit-risk consideration of the long-term use of clonazepam is important in pediatric patients. Use in Pregnancy & Lactation The use of clonazepam during pregnancy or lactation should be avoided. Clonazepam is excreted into the breast milk and should therefore be avoided in breast-feeding mothers. Drug Interaction Tablet: The CNS-depressant action of the benzodiazepine class of drugs may be potentiated by alcohol, narcotics, barbiturates, nonbarbiturate hypnotics, antianxiety agents, the phenothiazines, thioxanthene and butyrophenone classes of antipsychotic agents, monoamine oxidase inhibitors and the tricyclic antidepressants, and by other anticonvulsant drugs. Injection: The CNS-depressant action of the benzodiazepine class of drugs may be potentiated by alcohol, narcotics, barbiturates, nonbarbiturate hypnotics, antianxiety agents, the phenothiazines, thioxanthene and butyrophenone classes of antipsychotic agents, monoamine oxidase inhibitors and the tricyclic antidepressants, and by other anticonvulsant drugs. Over Dose Tablet: Symptoms of clonazepam overdosage, like those produced by other CNS depressants, include somnolence, confusion, coma and diminished reflexes. Injection: Symptoms of Clonazepam overdosage, like those produced by other CNS depressants, include: somnolence, confusion, coma and diminished reflexes. Commercial Pack Disopan 0.5 : Each box contains 10 blister strips of 10 tablets. Disopan 1 : Each tablet contains Clonazepam USP 1 mg. Disopan 2 : Each box contains 5 blister strips of 10 tablets. Disopan 1 injection: Each box contains a vial of Clonazepam 1 mg in 1 ml solution and 1ml ampoule of water for injection.

World No 1 Best selling Clonazepam tablet, side effect and more Disopan(Clonazepam) Presentation Disopan 0.5 : Each tablet contains Clonazepam USP 0.5 mg. Disopan 1 : Each tablet contains Clonazepam USP 1 mg. Disopan 2 : Each tablet contains Clonazepam USP 2 mg. Disopan 1 injection: Each vial contains Clonazepam USP 1 mg in 1 … Read more

World No 1 Best selling Arpolax(Citalopram) Tablet

Presentation Arpolax tablet: Each tablet contains Citalopram Hydrobromide INN equivalent to Citalopram 20 mg. Description Citalopram is an orally administered selective serotonin reuptake inhibitor (SSRI) with a chemical structure unrelated to that of other SSRIs, tricyclic, tetracyclic or other available antidepressant agents. The mechanism of action of Citalopram as an antidepressant is presumed to be linked to potentiation of serotonergic activity in central nervous system resulting from its inhibition of CNS neuronal reuptake of serotonin (5-HT). Indications Citalopram is indicated for depressive illness and panic disorder. It is also indicated in substance abuse disorders and alcohol dependence. Citalopram has also been given in variety of anxiety disorders including obsessive-compulsive disorder and social phobia. It is also effective in generalized anxiety disorder, post-traumatic stress disorder, premenstrual syndrome, idiopathic Parkinson's disease and eating disorder. Dosage & Administration Depressive illness 20 mg daily as a single dose in the morning or evening; increased if necessary to maximum 60 mg daily (Elderly maximum 40 mg daily). Panic disorder Initially 10 mg daily, increased to 20 mg after 7 days; usual dose 20- 30 mg daily; maximum 60 mg daily (Elderly maximum 40 mg daily). Side Effects SSRIs are less sedating and have fewer antimuscarinic and cardiotoxic effects than tricyclic antidepressants. However, side-effects may be seen, includes gastro-intestinal effects (nausea, vomiting, dyspepsia, abdominal pain, diarrhoea, constipation), anorexia with weight loss, palpitations, tachycardia, postural hypotension, cough, confusion, impaired concentration, amnesia, urinary retention, sweating, movement disorders, urticaria, anaphylaxis, arthralgia, myalgia and photosensitivity. Precautions Caution should be taken in patients with epilepsy, concurrent electroconvulsive therapy, history of mania, cardiac disease, diabetes mellitus, angle-closure glaucoma, history of bleeding disorders, hepatic and renal impairment. Abrupt withdrawal of Citalopram should be avoided. Use in Pregnancy & Lactation Pregnancy There are no adequate and well-controlled studies in pregnant women; therefore, Citalopram should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Lactation Citalopram is excreted in human breast milk. So, the decision whether to continue or discontinue either nursing or Citalopram therapy should take into account the risks of Citalopram exposure for the infants and the benefits of Citalopram treatment for the mother. Drug Interaction Ketoconazole, Itraconazole or Macrolide antibiotics and Citalopram co-administration decreases the metabolism of Citalopram. Omeprazole and Citalopram co-administration might decrease the clearance of Citalopram. Over Dose It is a very safe drug. There were no reports of fatal Citalopram overdose in clinical trials involving overdoses of up to 2000 mg. Commercial Pack Arpolax tablet: Box containing 3 blister strips of 10 tablets.

World No 1 Best selling Arpolax(Citalopram) Tablet Arpolax(Citalopram) Therapeutic Group: Drugs of Nervous System Presentation Arpolax tablet: Each tablet contains Citalopram Hydrobromide INN equivalent to Citalopram 20 mg. Description Citalopram is an orally administered selective serotonin reuptake inhibitor (SSRI) with a chemical structure unrelated to that of other SSRIs, tricyclic, tetracyclic or other available antidepressant … Read more

Best selling Ciprofloxacin, Ciprofloxacin side effects, ciprofloxacin uti and more

Beuflox(Ciprofloxacin)

Beuflox(Ciprofloxacin) Presentation Beuflox 250: Each film-coated tablet contains Ciprofloxacin Hydrochloride USP equivalent to Ciprofloxacin 250 mg. Beuflox 500: Each film-coated tablet contains Ciprofloxacin Hydrochloride USP equivalent to Ciprofloxacin 500 mg. Beuflox 750: Each film-coated tablet contains Ciprofloxacin Hydrochloride USP equivalent to Ciprofloxacin 750 mg. Beuflox 250 Granules for suspension: Each sachet contains Ciprofloxacin USP 250 … Read more

Cefixime Trihydrate USP : Emixef(Cefixime)

Cefixime Trihydrate USP : Emixef(Cefixime)

Cefixime Trihydrate USP : Emixef(Cefixime) Therapeutic Group: Cephalosporins Presentation Emixef 200 Capsule: Each capsule contains Cefixime Trihydrate USP equivalent to Cefixime 200 mg. Emixef 400 Capsule: Each capsule contains Cefixime Trihydrate USP equivalent to Cefixime 400 mg. Emixef Powder for Suspension: After reconstitution according to direction, each 5 ml suspension contains Cefixime Trihydrate USP equivalent … Read more

Best selling No1 Econazole Nitrate Cream : Uses, Side effects and more information

Econazole Nitrate Cream : Uses, Side effects and more information

Econazole Nitrate Cream Econate(Econazole Nitrate) Presentation Econate cream: Each gram cream contains Econazole Nitrate BP 10 mg. Econate-G cream: Each gram cream contains Econazole Nitrate BP 10 mg. Econate VT: Each vaginal tablet contains Econazole Nitrate BP 150 mg. Don’t Miss this : World best selling no.1 Ketoconazole Shampoo (Dancel Shampoo) Description Econazole Nitrate is … Read more